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Using Matched Molecular Series as a Predictive Tool To Optimize Biological Activity
[Image: see text] A matched molecular series is the general form of a matched molecular pair and refers to a set of two or more molecules with the same scaffold but different R groups at the same position. We describe Matsy, a knowledge-based method that uses matched series to predict R groups likel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968889/ https://www.ncbi.nlm.nih.gov/pubmed/24601597 http://dx.doi.org/10.1021/jm500022q |