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Effect of Spironolactone on Diabetic Nephropathy Compared to the Combination of Spironolactone and Losartan

BACKGROUND: Diabetic nephropathy is the most important cause of end stage renal disease (ESRD). Aldosterone is involved in renal damage through induction of fibrosis, inflammation and necrosis in the kidney tissue. Previous studies have demonstrated that the combination of angiotensin receptor block...

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Detalles Bibliográficos
Autores principales: Makhlough, Atieh, Kashi, Zahra, Akha, Ozra, Zaboli, Ehsan, Yazdanicharati, Jamshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968951/
https://www.ncbi.nlm.nih.gov/pubmed/24719811
http://dx.doi.org/10.5812/numonthly.12148