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Interactions of Morphine and Peptide 234 on Mean Plasma Testosterone Concentration

BACKGROUND: Kisspeptin-GPR54 system stimulates the hypothalamus-pituitary-gonadal (HPG) axis; dysfunction of the gene encoding the GPR54 receptor causes hypogonadism and infertility. Opioid peptides inhibit the reproductive axis. Peptide 234 is a GPR54 receptor antagonist and blocks the stimulatory...

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Detalles Bibliográficos
Autores principales: Mahmoudi, Fariba, Khazali, Homayoun, Janahmadi, Mahyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969002/
https://www.ncbi.nlm.nih.gov/pubmed/24696695
http://dx.doi.org/10.5812/ijem.12554