Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology

BACKGROUND AND PURPOSE: Receptor activity-modifying proteins (RAMPs) define the pharmacology of the calcitonin receptor-like receptor (CLR). The interactions of the different RAMPs with this class B GPCR yield high-affinity calcitonin gene-related peptide (CGRP) or adrenomedullin (AM) receptors. How...

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Detalles Bibliográficos
Autores principales: Watkins, H A, Walker, C S, Ly, K N, Bailey, R J, Barwell, J, Poyner, D R, Hay, D L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Journal of Pharmacology 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969088/
https://www.ncbi.nlm.nih.gov/pubmed/24199627
http://dx.doi.org/10.1111/bph.12508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969088/
https://www.ncbi.nlm.nih.gov/pubmed/24199627
http://dx.doi.org/10.1111/bph.12508

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