Cdk1 Inactivation Terminates Mitotic Checkpoint Surveillance and Stabilizes Kinetochore Attachments in Anaphase

Two mechanisms safeguard the bipolar attachment of chromosomes in mitosis. A correction mechanism destabilizes erroneous attachments that do not generate tension across sister kinetochores [1]. In response to unattached kinetochores, the mitotic checkpoint delays anaphase onset by inhibiting the ana...

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Detalles Bibliográficos
Autores principales: Vázquez-Novelle, María Dolores, Sansregret, Laurent, Dick, Amalie E., Smith, Christopher A., McAinsh, Andrew D., Gerlich, Daniel W., Petronczki, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969148/
https://www.ncbi.nlm.nih.gov/pubmed/24583019
http://dx.doi.org/10.1016/j.cub.2014.01.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969148/
https://www.ncbi.nlm.nih.gov/pubmed/24583019
http://dx.doi.org/10.1016/j.cub.2014.01.034

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