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Cdk1 Inactivation Terminates Mitotic Checkpoint Surveillance and Stabilizes Kinetochore Attachments in Anaphase

Two mechanisms safeguard the bipolar attachment of chromosomes in mitosis. A correction mechanism destabilizes erroneous attachments that do not generate tension across sister kinetochores [1]. In response to unattached kinetochores, the mitotic checkpoint delays anaphase onset by inhibiting the ana...

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Detalles Bibliográficos
Autores principales:	Vázquez-Novelle, María Dolores, Sansregret, Laurent, Dick, Amalie E., Smith, Christopher A., McAinsh, Andrew D., Gerlich, Daniel W., Petronczki, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969148/ https://www.ncbi.nlm.nih.gov/pubmed/24583019 http://dx.doi.org/10.1016/j.cub.2014.01.034

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