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Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis
Normal hemostasis requires von Willebrand factor (VWF) to support platelet adhesion and aggregation at sites of vascular injury. VWF is a multimeric glycoprotein built from identical subunits that contain binding sites for both platelet glycoprotein receptors and collagen. The adhesive activity of V...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams And Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969155/ https://www.ncbi.nlm.nih.gov/pubmed/24448155 http://dx.doi.org/10.1097/MBC.0000000000000065 |