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N-terminus oligomerization is conserved in intracellular calcium release channels
Oligomerization of all three mammalian ryanodine receptor isoforms, a structural requirement for normal intracellular Ca(2+) release channel function, is displayed by the discrete N-terminal domain which assembles into homo- and hetero-tetramers. This is demonstrated in yeast, mammalian cells and na...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969220/ https://www.ncbi.nlm.nih.gov/pubmed/24502647 http://dx.doi.org/10.1042/BJ20131061 |