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Bacillus thuringiensis Cry1A toxins are versatile proteins with multiple modes of action: two distinct pre-pores are involved in toxicity

Cry proteins from Bacillus thuringiensis are insecticidal PFTs (pore-forming toxins). In the present study, we show that two distinct functional pre-pores of Cry1Ab are formed after binding of the protoxin or the protease-activated toxin to the cadherin receptor, but before membrane insertion. Both...

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Detalles Bibliográficos
Autores principales: Gómez, Isabel, Sánchez, Jorge, Muñoz-Garay, Carlos, Matus, Violeta, Gill, Sarjeet S., Soberón, Mario, Bravo, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969221/
https://www.ncbi.nlm.nih.gov/pubmed/24456341
http://dx.doi.org/10.1042/BJ20131408