Cargando…

Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase

Co- and post-translational N-myristoylation is known to play a role in the correct subcellular localization of specific proteins in eukaryotes. The enzyme that catalyses this reaction, NMT (N-myristoyltransferase), has been pharmacologically validated as a drug target in the African trypanosome, Try...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, Adam J., Torrie, Leah S., Wyllie, Susan, Fairlamb, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969225/
https://www.ncbi.nlm.nih.gov/pubmed/24444291
http://dx.doi.org/10.1042/BJ20131033