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Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells

The concept of cancer stem cells has gained considerable interest in the last few decades, partly because of their potential implication in therapy resistance. However, the lack of specific cellular surface markers for these cells has impeded their isolation, making the characterization of this cell...

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Detalles Bibliográficos
Autores principales: Nakata, Susumu, Phillips, Emma, Goidts, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969255/
https://www.ncbi.nlm.nih.gov/pubmed/24711713
http://dx.doi.org/10.2147/CMAR.S57846