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Localization-Dependent and -Independent Roles of SLX4 in Regulating Telomeres

SLX4, a scaffold for structure-specific DNA repair nucleases, is important for several types of DNA repair. Many repair proteins bind to sites of DNA damage, resulting in subnuclear “foci,” but SLX4 forms foci in human cells even without DNA damage. Using several approaches, we show that most, but n...

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Detalles Bibliográficos
Autores principales: Wilson, Jamie S.J., Tejera, Agueda M., Castor, Dennis, Toth, Rachel, Blasco, Maria A., Rouse, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969258/
https://www.ncbi.nlm.nih.gov/pubmed/23994477
http://dx.doi.org/10.1016/j.celrep.2013.07.033