Cargando…
Localization-Dependent and -Independent Roles of SLX4 in Regulating Telomeres
SLX4, a scaffold for structure-specific DNA repair nucleases, is important for several types of DNA repair. Many repair proteins bind to sites of DNA damage, resulting in subnuclear “foci,” but SLX4 forms foci in human cells even without DNA damage. Using several approaches, we show that most, but n...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969258/ https://www.ncbi.nlm.nih.gov/pubmed/23994477 http://dx.doi.org/10.1016/j.celrep.2013.07.033 |