Cargando…

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936()

Apolipoprotein E (APOE) ε genotype has previously been significantly associated with cognitive, brain imaging, and Alzheimer's disease-related phenotypes (e.g., age of onset). In the TOMM40 gene, the rs10524523 (“523”) variable length poly-T repeat polymorphism has more recently been associated...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyall, Donald M., Harris, Sarah E., Bastin, Mark E., Muñoz Maniega, Susana, Murray, Catherine, Lutz, Michael W., Saunders, Ann M., Roses, Allen D., Valdés Hernández, Maria del C., Royle, Natalie A., Starr, John M., Porteous, David. J., Wardlaw, Joanna M., Deary, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969262/
https://www.ncbi.nlm.nih.gov/pubmed/24508314
http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.006