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Assessment of Targeted and Non-Targeted Responses in Cells Deficient in ATM Function following Exposure to Low and High Dose X-Rays

Radiation sensitivity at low and high dose exposure to X-rays was investigated by means of chromosomal aberration (CA) analysis in heterozygous ATM mutation carrier and A-T patient (biallelic ATM mutation) lymphoblastoid cell lines (LCLs). Targeted and non-targeted responses to acutely delivered irr...

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Detalles Bibliográficos
Autores principales: Kiuru, Anne, Kämäräinen, Meerit, Heinävaara, Sirpa, Pylkäs, Katri, Chapman, Kim, Koivistoinen, Armi, Parviainen, Teuvo, Winqvist, Robert, Kadhim, Munira, Launonen, Virpi, Lindholm, Carita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969311/
https://www.ncbi.nlm.nih.gov/pubmed/24681528
http://dx.doi.org/10.1371/journal.pone.0093211