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A Liver-X-Receptor Ligand, T0901317, Attenuates IgE Production and Airway Remodeling in Chronic Asthma Model of Mice

The liver-X-receptors have shown anti-inflammatory ability in several animal models of respiratory disease. Our purpose is to investigate the effect of LXR ligand in allergen-induced airway remodeling in mice. Ovalbumin-sensitized mice were chronically challenged with aerosolized ovalbumin for 8 wee...

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Detalles Bibliográficos
Autores principales: Shi, Ying, Xu, Xiantao, Tan, Yan, Mao, Shan, Fang, Surong, Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969355/
https://www.ncbi.nlm.nih.gov/pubmed/24681543
http://dx.doi.org/10.1371/journal.pone.0092668