Radiosynthesis and Biological Evaluation of N-[(18)F]Labeled Glutamic Acid as a Tumor Metabolic Imaging Tracer

We have previously reported that N-(2-[(18)F]fluoropropionyl)-L-methionine ([(18)F]FPMET) selectively accumulates in tumors. However, due to the poor pharmacokinetics of [(18)F]FPMET in vivo, the potential clinical translation of this observation is hampered. In this study, we rationally designed an...

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Detalles Bibliográficos
Autores principales: Hu, Kongzhen, Du, Kan, Tang, Ganghua, Yao, Shaobo, Wang, Hongliang, Liang, Xiang, Yao, Baoguo, Huang, Tingting, Zang, Linquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969356/
https://www.ncbi.nlm.nih.gov/pubmed/24681642
http://dx.doi.org/10.1371/journal.pone.0093262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969356/
https://www.ncbi.nlm.nih.gov/pubmed/24681642
http://dx.doi.org/10.1371/journal.pone.0093262

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