A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells

Changes in the levels of specific microRNAs (miRNAs) can reduce glucose-stimulated insulin secretion and increase beta-cell apoptosis, two causes of islet dysfunction and progression to type 2 diabetes. Studies have shown that single nucleotide polymorphisms (SNPs) within miRNA genes can affect thei...

Descripción completa

Detalles Bibliográficos
Autores principales: Locke, Jonathan M., Lango Allen, Hana, Harries, Lorna W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969511/
https://www.ncbi.nlm.nih.gov/pubmed/23828613
http://dx.doi.org/10.1007/s00592-013-0499-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969511/
https://www.ncbi.nlm.nih.gov/pubmed/23828613
http://dx.doi.org/10.1007/s00592-013-0499-1

Ejemplares similares