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A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells

Changes in the levels of specific microRNAs (miRNAs) can reduce glucose-stimulated insulin secretion and increase beta-cell apoptosis, two causes of islet dysfunction and progression to type 2 diabetes. Studies have shown that single nucleotide polymorphisms (SNPs) within miRNA genes can affect thei...

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Detalles Bibliográficos
Autores principales:	Locke, Jonathan M., Lango Allen, Hana, Harries, Lorna W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Milan 2013
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969511/ https://www.ncbi.nlm.nih.gov/pubmed/23828613 http://dx.doi.org/10.1007/s00592-013-0499-1

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