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Differentiation of Human Epidermal Neural Crest Stem Cells (hEPI-NCSC) into Virtually Homogenous Populations of Dopaminergic Neurons

Here we provide a protocol for the directed differentiation of hEPI-NCSC into midbrain dopaminergic neurons, which degenerate in Parkinson’s disease. hEPI-NCSC are neural crest-derived multipotent stem cells that persist into adulthood in the bulge of hair follicles. The experimental design is disti...

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Detalles Bibliográficos
Autores principales: Narytnyk, Alla, Verdon, Bernard, Loughney, Andrew, Sweeney, Michele, Clewes, Oliver, Taggart, Michael J., Sieber-Blum, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969515/
https://www.ncbi.nlm.nih.gov/pubmed/24399192
http://dx.doi.org/10.1007/s12015-013-9493-9