N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response

N(6)-isopentenyladenosine (i(6)A), a naturally occurring modified nucleoside, inhibits the proliferation of human tumor cell lines in vitro, but its mechanism of action remains unclear. Treatment of MCF7 human breast adenocarcinoma cells with i(6)A or with three synthetic analogs (allyl(6)A, benzyl(...

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Detalles Bibliográficos
Autores principales: Dassano, Alice, Mancuso, Mariateresa, Giardullo, Paola, Cecco, Loris De, Ciuffreda, Pierangela, Santaniello, Enzo, Saran, Anna, Dragani, Tommaso A., Colombo, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969604/
https://www.ncbi.nlm.nih.gov/pubmed/24688894
http://dx.doi.org/10.1016/j.redox.2014.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969604/
https://www.ncbi.nlm.nih.gov/pubmed/24688894
http://dx.doi.org/10.1016/j.redox.2014.03.001

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