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c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1
Angiogenesis is regulated by highly coordinated action of various proteins with pro- and anti-angiogenic functions. Among the many cytoplasmic signaling proteins that are activated by VEGFR-2, activation of PLCγ1 is considered to play a pivotal role in angiogenic signaling. In previous study we have...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969724/ https://www.ncbi.nlm.nih.gov/pubmed/21242968 http://dx.doi.org/10.1038/onc.2010.597 |