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Interferon-alpha-2b induces autophagy in hepatocellular carcinoma cells through Beclin1 pathway
OBJECTIVE: To determine whether Interferon-alpha-2b (IFN-α2b) can modulate the autophagic response in hepatocellular carcinoma cells. METHODS: Hepatocellular carcinoma cells were treated with IFN-α2b. Autophagy was assessed by acridine orange staining, GFP-LC3 dotted assay, transmission electron mic...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Anti-Cancer Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969804/ https://www.ncbi.nlm.nih.gov/pubmed/24738040 http://dx.doi.org/10.7497/j.issn.2095-3941.2014.01.006 |