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Interferon-alpha-2b induces autophagy in hepatocellular carcinoma cells through Beclin1 pathway

OBJECTIVE: To determine whether Interferon-alpha-2b (IFN-α2b) can modulate the autophagic response in hepatocellular carcinoma cells. METHODS: Hepatocellular carcinoma cells were treated with IFN-α2b. Autophagy was assessed by acridine orange staining, GFP-LC3 dotted assay, transmission electron mic...

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Detalles Bibliográficos
Autores principales: Zhao, Jun, Wang, Ming-Li, Li, Zeng, Gao, Dong-Mei, Cai, Yu, Chang, Jun, Wang, Shi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969804/
https://www.ncbi.nlm.nih.gov/pubmed/24738040
http://dx.doi.org/10.7497/j.issn.2095-3941.2014.01.006