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A Cell-Based Pharmacokinetics Assay for Evaluating Tubulin-Binding Drugs
Increasing evidence reveals that traditional pharmacokinetics parameters based on plasma drug concentrations are insufficient to reliably demonstrate accurate pharmacological effects of drugs in target organs or cells in vivo. This underscores the increasing need to improve the types and qualities o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970101/ https://www.ncbi.nlm.nih.gov/pubmed/24688312 http://dx.doi.org/10.7150/ijms.8340 |