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Playing Hide and Seek: How Glycosylation of the Influenza Virus Hemagglutinin Can Modulate the Immune Response to Infection

Seasonal influenza A viruses (IAV) originate from pandemic IAV and have undergone changes in antigenic structure, including addition of glycans to the hemagglutinin (HA) glycoprotein. The viral HA is the major target recognized by neutralizing antibodies and glycans have been proposed to shield anti...

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Detalles Bibliográficos
Autores principales: Tate, Michelle D., Job, Emma R., Deng, Yi-Mo, Gunalan, Vithiagaran, Maurer-Stroh, Sebastian, Reading, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970151/
https://www.ncbi.nlm.nih.gov/pubmed/24638204
http://dx.doi.org/10.3390/v6031294