Single-Dose Intranasal Treatment with DEF201 (Adenovirus Vectored Consensus Interferon) Prevents Lethal Disease Due to Rift Valley Fever Virus Challenge

Rift Valley fever virus (RVFV) causes severe disease in humans and ungulates. The virus can be transmitted by mosquitoes, direct contact with infected tissues or fluids, or aerosol, making it a significant biological threat for which there is no approved vaccine or therapeutic. Herein we describe th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gowen, Brian B., Ennis, Jane, Bailey, Kevin W., Vest, Zachary, Scharton, Dionna, Sefing, Eric J., Turner, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970158/
https://www.ncbi.nlm.nih.gov/pubmed/24662673
http://dx.doi.org/10.3390/v6031410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970158/
https://www.ncbi.nlm.nih.gov/pubmed/24662673
http://dx.doi.org/10.3390/v6031410

Ejemplares similares