Liver-primed CD8(+) T cells suppress antiviral adaptive immunity through galectin-9-independent T-Cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice

The liver is a tolerogenic environment exploited by persistent infections, such as hepatitis B (HBV) and C (HCV) viruses. In a murine model of intravenous hepatotropic adenovirus infection, liver-primed antiviral CD8(+) T cells fail to produce proinflammatory cytokines and do not display cytolytic a...

Descripción completa

Detalles Bibliográficos
Autores principales: Dolina, Joseph S, Braciale, Thomas J, Hahn, Young S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Viral Hepatitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970181/
https://www.ncbi.nlm.nih.gov/pubmed/24677194
http://dx.doi.org/10.1002/hep.26938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970181/
https://www.ncbi.nlm.nih.gov/pubmed/24677194
http://dx.doi.org/10.1002/hep.26938

Ejemplares similares