Non-random DNA fragmentation in next-generation sequencing

Next Generation Sequencing (NGS) technology is based on cutting DNA into small fragments, and their massive parallel sequencing. The multiple overlapping segments termed “reads” are assembled into a contiguous sequence. To reduce sequencing errors, every genome region should be sequenced several doz...

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Detalles Bibliográficos
Autores principales: Poptsova, Maria S., Il'icheva, Irina A., Nechipurenko, Dmitry Yu., Panchenko, Larisa A., Khodikov, Mingian V., Oparina, Nina Y., Polozov, Robert V., Nechipurenko, Yury D., Grokhovsky, Sergei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970190/
https://www.ncbi.nlm.nih.gov/pubmed/24681819
http://dx.doi.org/10.1038/srep04532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970190/
https://www.ncbi.nlm.nih.gov/pubmed/24681819
http://dx.doi.org/10.1038/srep04532

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