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Non-random DNA fragmentation in next-generation sequencing
Next Generation Sequencing (NGS) technology is based on cutting DNA into small fragments, and their massive parallel sequencing. The multiple overlapping segments termed “reads” are assembled into a contiguous sequence. To reduce sequencing errors, every genome region should be sequenced several doz...
Autores principales: | Poptsova, Maria S., Il'icheva, Irina A., Nechipurenko, Dmitry Yu., Panchenko, Larisa A., Khodikov, Mingian V., Oparina, Nina Y., Polozov, Robert V., Nechipurenko, Yury D., Grokhovsky, Sergei L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970190/ https://www.ncbi.nlm.nih.gov/pubmed/24681819 http://dx.doi.org/10.1038/srep04532 |
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