Ca(2+)-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

Phospholipid scramblases disrupt the lipid asymmetry of the plasma membrane, externalizing phosphatidylserine to trigger blood coagulation and mark apoptotic cells. Recently, members of the TMEM16 family of Ca(2+)-gated channels have been shown to be involved in Ca(2+)-dependent scrambling. It is ho...

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Detalles Bibliográficos
Autores principales: Malvezzi, Mattia, Chalat, Madhavan N., Janjusevic, Radmila, Picollo, Alessandra, Terashima, Hiroyuki, Menon, Anant K., Accardi, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970400/
https://www.ncbi.nlm.nih.gov/pubmed/23996062
http://dx.doi.org/10.1038/ncomms3367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970400/
https://www.ncbi.nlm.nih.gov/pubmed/23996062
http://dx.doi.org/10.1038/ncomms3367

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