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Ca(2+)-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel
Phospholipid scramblases disrupt the lipid asymmetry of the plasma membrane, externalizing phosphatidylserine to trigger blood coagulation and mark apoptotic cells. Recently, members of the TMEM16 family of Ca(2+)-gated channels have been shown to be involved in Ca(2+)-dependent scrambling. It is ho...
Autores principales: | Malvezzi, Mattia, Chalat, Madhavan N., Janjusevic, Radmila, Picollo, Alessandra, Terashima, Hiroyuki, Menon, Anant K., Accardi, Alessio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970400/ https://www.ncbi.nlm.nih.gov/pubmed/23996062 http://dx.doi.org/10.1038/ncomms3367 |
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