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Biodistribution of meglumine antimoniate in healthy and Leishmania (Leishmania) infantum chagasi-infected BALB/c mice

Pentavalent antimonials such as meglumine antimoniate (MA) are the primary treatments for leishmaniasis, a complex disease caused by protozoan parasites of the genus Leishmania . Despite over 70 years of clinical use, their mechanisms of action, toxicity and pharmacokinetics have not been fully eluc...

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Detalles Bibliográficos
Autores principales: Borborema, Samanta Etel Treiger, Osso, João Alberto, de Andrade, Heitor Franco, do Nascimento, Nanci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970594/
https://www.ncbi.nlm.nih.gov/pubmed/23903979
http://dx.doi.org/10.1590/0074-0276108052013014