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Progressive right ventricular functional and structural changes in a mouse model of pulmonary arterial hypertension

Right ventricle (RV) dysfunction occurs with progression of pulmonary arterial hypertension (PAH) due to persistently elevated ventricular afterload. A critical knowledge gap is the molecular mechanisms that govern the transition from RV adaptation to RV maladaptation, which leads to failure. Here,...

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Detalles Bibliográficos
Autores principales: Wang, Zhijie, Schreier, David A., Hacker, Timothy A., Chesler, Naomi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970737/
https://www.ncbi.nlm.nih.gov/pubmed/24744862
http://dx.doi.org/10.1002/phy2.184