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Thrombin‐mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension

Chronic thromboembolic pulmonary hypertension (CTEPH) has been increasingly recognized as a common source of elevated pulmonary vascular resistance and pulmonary hypertension. It is clear that development of pulmonary thromboemboli is the inciting event for this process, yet it remains unclear why s...

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Detalles Bibliográficos
Autores principales: Ogawa, Aiko, Firth, Amy L., Ariyasu, Sanae, Yamadori, Ichiro, Matsubara, Hiromi, Song, Shanshan, Fraidenburg, Dustin R., Yuan, Jason X.‐J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970741/
https://www.ncbi.nlm.nih.gov/pubmed/24744867
http://dx.doi.org/10.1002/phy2.190