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A new twist on an old idea: a two‐dimensional speckle tracking assessment of cyclosporine as a therapeutic alternative for heart failure with preserved ejection fraction

We recently reported that mitochondrial dysfunction, characterized by increased mitochondrial permeability transition (MPT), was present in a translational swine model of heart failure with preserved ejection fraction (HFpEF). Cyclophilin D is a key component of the MPT pore, therefore, the purpose...

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Detalles Bibliográficos
Autores principales: Hiemstra, Jessica A., Liu, Songtao, Ahlman, Mark A., Schuleri, Karl H., Lardo, Albert C., Baines, Christopher P., Dellsperger, Kevin C., Bluemke, David A., Emter, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970750/
https://www.ncbi.nlm.nih.gov/pubmed/24744855
http://dx.doi.org/10.1002/phy2.174