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Sequence variation and structural conservation allows development of novel function and immune evasion in parasite surface protein families

Trypanosoma and Plasmodium species are unicellular, eukaryotic pathogens that have evolved the capacity to survive and proliferate within a human host, causing sleeping sickness and malaria, respectively. They have very different survival strategies. African trypanosomes divide in blood and extracel...

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Detalles Bibliográficos
Autores principales: Higgins, Matthew K, Carrington, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Blackwell 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970887/
https://www.ncbi.nlm.nih.gov/pubmed/24442723
http://dx.doi.org/10.1002/pro.2428