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Synthesis of ciprofloxacin-conjugated poly (L-lactic acid) polymer for nanofiber fabrication and antibacterial evaluation

Ciprofloxacin was conjugated with polylactide (PLA) via the secondary amine group of the piperazine ring using PLA and 7-(4-(2-Chloroacetyl) piperazin-1-yl)-1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid. Zinc prolinate, a biocompatible catalyst was synthesized, characterized,...

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Detalles Bibliográficos
Autores principales: Parwe, Sharad P, Chaudhari, Priti N, Mohite, Kavita K, Selukar, Balaji S, Nande, Smita S, Garnaik, Baijayantimala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970946/
https://www.ncbi.nlm.nih.gov/pubmed/24741303
http://dx.doi.org/10.2147/IJN.S54971