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An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer
Poor prognosis oestrogen receptor positive breast cancer is characterized by the presence of high-level focal amplifications. We utilized a focused siRNA screen in 14 breast cancer cell lines to define genes that were pathogenic in three genomic regions focally amplified in oestrogen receptor positi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970970/ https://www.ncbi.nlm.nih.gov/pubmed/23752180 http://dx.doi.org/10.1038/onc.2013.202 |