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BAIT: Organizing genomes and mapping rearrangements in single cells

Strand-seq is a single-cell sequencing technique to finely map sister chromatid exchanges (SCEs) and other rearrangements. To analyze these data, we introduce BAIT, software which assigns templates and identifies and localizes SCEs. We demonstrate BAIT can refine completed reference assemblies, iden...

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Detalles Bibliográficos
Autores principales: Hills, Mark, O’Neill, Kieran, Falconer, Ester, Brinkman, Ryan, Lansdorp, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971352/
https://www.ncbi.nlm.nih.gov/pubmed/24028793
http://dx.doi.org/10.1186/gm486