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BAIT: Organizing genomes and mapping rearrangements in single cells
Strand-seq is a single-cell sequencing technique to finely map sister chromatid exchanges (SCEs) and other rearrangements. To analyze these data, we introduce BAIT, software which assigns templates and identifies and localizes SCEs. We demonstrate BAIT can refine completed reference assemblies, iden...
Autores principales: | Hills, Mark, O’Neill, Kieran, Falconer, Ester, Brinkman, Ryan, Lansdorp, Peter M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971352/ https://www.ncbi.nlm.nih.gov/pubmed/24028793 http://dx.doi.org/10.1186/gm486 |
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