Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis

The inhibition of triosephosphate isomerase (TPI) in glycolysis by the pyruvate kinase (PK) substrate phosphoenolpyruvate (PEP) results in a newly discovered feedback loop that counters oxidative stress in cancer and actively respiring cells. The mechanism underlying this inhibition is illuminated b...

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Detalles Bibliográficos
Autores principales: Grüning, Nana-Maria, Du, Dijun, Keller, Markus A., Luisi, Ben F., Ralser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971408/
https://www.ncbi.nlm.nih.gov/pubmed/24598263
http://dx.doi.org/10.1098/rsob.130232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971408/
https://www.ncbi.nlm.nih.gov/pubmed/24598263
http://dx.doi.org/10.1098/rsob.130232

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