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Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis
The inhibition of triosephosphate isomerase (TPI) in glycolysis by the pyruvate kinase (PK) substrate phosphoenolpyruvate (PEP) results in a newly discovered feedback loop that counters oxidative stress in cancer and actively respiring cells. The mechanism underlying this inhibition is illuminated b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971408/ https://www.ncbi.nlm.nih.gov/pubmed/24598263 http://dx.doi.org/10.1098/rsob.130232 |