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Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery

Hypoxia-inducible factor 1α (HIF1α) activates the transcription of genes that are involved in angiogenesis and cell survival. Over-expression of HIF1α caused by intratumoral hypoxia and its genetic alterations are associated with increased mortality in several cancer types including non-small-cell l...

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Detalles Bibliográficos
Autores principales: Liu, Boya, Liu, Qingchun, Song, Yang, Li, Xiaofei, Wang, Yunjie, Wan, Shaogui, Zhang, Zhipei, Su, Haichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971443/
https://www.ncbi.nlm.nih.gov/pubmed/24567056
http://dx.doi.org/10.1007/s12032-014-0877-8