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Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery
Hypoxia-inducible factor 1α (HIF1α) activates the transcription of genes that are involved in angiogenesis and cell survival. Over-expression of HIF1α caused by intratumoral hypoxia and its genetic alterations are associated with increased mortality in several cancer types including non-small-cell l...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971443/ https://www.ncbi.nlm.nih.gov/pubmed/24567056 http://dx.doi.org/10.1007/s12032-014-0877-8 |