Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262

In the ER (endoplasmic reticulum) of human cells, disulfide bonds are predominantly generated by the two isoforms of Ero1 (ER oxidoreductin-1): Ero1α and Ero1β. The activity of Ero1α is tightly regulated through the formation of intramolecular disulfide bonds to help ensure balanced ER redox conditi...

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Detalles Bibliográficos
Autores principales: Hansen, Henning G., Søltoft, Cecilie L., Schmidt, Jonas D., Birk, Julia, Appenzeller-Herzog, Christian, Ellgaard, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971451/
https://www.ncbi.nlm.nih.gov/pubmed/27919037
http://dx.doi.org/10.1042/BSR20130124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971451/
https://www.ncbi.nlm.nih.gov/pubmed/27919037
http://dx.doi.org/10.1042/BSR20130124

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