Global Footprints of Purifying Selection on Toll-Like Receptor Genes Primarily Associated with Response to Bacterial Infections in Humans

Toll-like receptors (TLRs) are directly involved in host–pathogen interactions. Polymorphisms in these genes are associated with susceptibility to infectious diseases. To understand the influence of environment and pathogen diversity on the evolution of TLR genes, we have undertaken a large-scale po...

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Detalles Bibliográficos
Autores principales: Mukherjee, Souvik, Ganguli, Debdutta, Majumder, Partha P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971583/
https://www.ncbi.nlm.nih.gov/pubmed/24554585
http://dx.doi.org/10.1093/gbe/evu032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971583/
https://www.ncbi.nlm.nih.gov/pubmed/24554585
http://dx.doi.org/10.1093/gbe/evu032

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