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Route, mechanism, and implications of proton import during Na(+)/K(+) exchange by native Na(+)/K(+)-ATPase pumps
A single Na(+)/K(+)-ATPase pumps three Na(+) outwards and two K(+) inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na(+) than K(+) generates ou...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971657/ https://www.ncbi.nlm.nih.gov/pubmed/24688018 http://dx.doi.org/10.1085/jgp.201311148 |