TAp73 is essential for germ cell adhesion and maturation in testis

A core evolutionary function of the p53 family is to protect the genomic integrity of gametes. However, the role of p73 in the male germ line is unknown. Here, we reveal that TAp73 unexpectedly functions as an adhesion and maturation factor of the seminiferous epithelium orchestrating spermiogenesis...

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Detalles Bibliográficos
Autores principales: Holembowski, Lena, Kramer, Daniela, Riedel, Dietmar, Sordella, Raffaella, Nemajerova, Alice, Dobbelstein, Matthias, Moll, Ute M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971741/
https://www.ncbi.nlm.nih.gov/pubmed/24662569
http://dx.doi.org/10.1083/jcb.201306066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971741/
https://www.ncbi.nlm.nih.gov/pubmed/24662569
http://dx.doi.org/10.1083/jcb.201306066

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