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Lowered Insulin Signalling Ameliorates Age-Related Sleep Fragmentation in Drosophila

Sleep fragmentation, particularly reduced and interrupted night sleep, impairs the quality of life of older people. Strikingly similar declines in sleep quality are seen during ageing in laboratory animals, including the fruit fly Drosophila. We investigated whether reduced activity of the nutrient-...

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Detalles Bibliográficos
Autores principales: Metaxakis, Athanasios, Tain, Luke S., Grönke, Sebastian, Hendrich, Oliver, Hinze, Yvonne, Birras, Ulrike, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972082/
https://www.ncbi.nlm.nih.gov/pubmed/24690889
http://dx.doi.org/10.1371/journal.pbio.1001824