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A Structure-Based Model for Predicting Serum Albumin Binding

One of the many factors involved in determining the distribution and metabolism of a compound is the strength of its binding to human serum albumin. While experimental and QSAR approaches for determining binding to albumin exist, various factors limit their ability to provide accurate binding affini...

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Detalles Bibliográficos
Autores principales: Lexa, Katrina W., Dolghih, Elena, Jacobson, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972100/
https://www.ncbi.nlm.nih.gov/pubmed/24691448
http://dx.doi.org/10.1371/journal.pone.0093323