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Beta2 Adrenergic Receptor (ADRβ2) Haplotype Pair (2/4) Is Associated with Severe Asthma

BACKGROUND: β2 adrenergic receptor (ADRβ2) polymorphisms including ADRβ2+46G>A have been reported to cause adverse outcomes in mild asthmatics. The extent to which ADRβ2 polymorphisms and in particular their haplotypes contribute to severe asthma is unknown. OBJECTIVE: To determine the associatio...

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Detalles Bibliográficos
Autores principales: Chung, Li Ping, Baltic, Svetlana, Ferreira, Manuel, Temple, Suzanna, Waterer, Grant, Thompson, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972120/
https://www.ncbi.nlm.nih.gov/pubmed/24691493
http://dx.doi.org/10.1371/journal.pone.0093695